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Review:Transcriptional Repression by Histone Deacetylases in Plants  

2014-05-08 08:48:36|  分类: 文献学习 |  标签: |举报 |字号 订阅

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Reversible histone acetylation and deacetylation at the N-terminus of histone tails play crucial roles in regulation of eukaryotic gene activity. Acetylation of core histones usually induces an ‘open’ chromatin structure and is associated with gene activation, whereas deacetylation of histone is often correlated with ‘closed’ chromatin and gene repression. Histone deacetylation is catalyzed by histone deacetylases (HDACs). A growing number of studies have demonstrated the importance of histone deacetylation/acetylation on genome stability, transcriptional regulation, and development in plants. Furthermore, HDACs were shown to interact with various chromatin remolding factors and transcription factors involved in transcriptional repression in multiple developmental processes. In this review, we summarized recent findings on the transcriptional repression mediated by HDACs in plants.
Review:Transcriptional Repression by Histone Deacetylases in Plants - 喜欢吃桃子 - wangyufeng的博客

 Figure 1

Transcriptional Repression Mediated by HDACs in Arabidopsis.

(A) HDA6 represses gene expression by interacting with various transcription factors and co-repressors involved in flowering time, leaf development, and circadian clock.

(B) HDA19 represses gene expression involved in seed maturation and flower development.

(C) PIF3 interacts with HDA15 to repress chlorophyll biosynthetic genes.

Citation:Liu X, Yang S, Zhao M, Luo M, Yu C-W, Chen C-Y, Tai R, Wu K: Transcriptional Repression by Histone Deacetylases in Plants. Molecular Plant 2014, 7(5):764-772.

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