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QTL Analysis Software Tools for Illumina Data  

2011-10-27 09:10:05|  分类: 数量遗传学 |  标签: |举报 |字号 订阅

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        Combining the results from the wide range of Illumina genetic analysis assays is a powerful integrated approach for complex questions. Illumina provides data analysis software that supports data integration, such as genotyping with gene expression for eQTL analysis.
       In the past few years, researchers have used Illumina DNA Analysis BeadChips in genome-wide association studies (GWAS) to make numerous discoveries uncovering the genetic basis of common diseases. As geneticists turn toward elucidating the causes of more complex diseases, it is expected that associated variants will be rarer and pleiotropic phenotypes will be more common. Given these complicating factors, a typical GWAS experimental design may not be ideal. Several recent studies have suggested that an approach integrating expression profiling with genotyping—referred to as eQTL (expression quantitative trait locus) analysis—may be more powerful.

You can download full text form:
http://www.illumina.com/Documents/products/technotes/technote_gtl_software.pdf
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