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Simulating systems genetics data with SysGenSIM  

2011-10-20 12:31:27|  分类: 数量遗传学 |  标签: |举报 |字号 订阅

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What is SysGenSIM?

      SysGenSIM is a bioinformatics toolbox for MATLAB? to create artificial gene expression datasets by simulating Systems Genetics experiments.

Requirements

To run SysGenSIM you need Mathworks MATLAB? version 7.9 (R2009b) or later, with Bioinformatics and Statistics toolboxes.

SysGenSIM has been developed by: Andrea Pinna, Nicola Soranzo, Ina Hoeschele, Alberto de la Fuente.

Summary: SysGenSIM is a software package to simulate Systems Genetics (SG) experiments in model organisms, for the purpose of evaluating and comparing statistical and computational methods and their implementations for analyses of SG data (e.g., methods for Expression Quantitative Trait Loci (eQTL) mapping and network inference). SysGenSIM allows the user to select a variety of network topologies, genetic and kinetic parameters to simulate SG data (genotyping, gene expression and phenotyping) with large gene networks with thousands of nodes. The software is encoded in MATLAB, and a user-friendly Graphical User Interface is provided.

Availability: The open-source software code and user manual can be downloaded at: http://sysgensim.sourceforge.net/

Contact: alf@crs4.it


 

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